Research archive · This publication is preserved from the LEMMO Cancer Care library. Findings are specific to the study design and population and may not reflect current clinical practice.
1990, Vol. 6, No. 3 , Pages 479-486
N. R. Datta1†, A. K. Bose1,23, H. K. Kapoor1,23 and S. Gupta1,23
1Department of Radiotherapy, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
2Department of Radiotherapy, Maulana Azad Medical College and associated Lok Nayak Jai Prakash Narain, New Delhi, India
3G. B. Pant Hospital, New Delhi, India
†Correspondence: N. R. Datta, Department of Radiotherapy, Sanjay Gandhi Post Graduate Institute of Medical Sciences, P.B. No. 375, Lucknow, 226001, India
Sixty-five patients were included in a randomized clinical study to evaluate the efficacy of local hyperthermia as a concomitant agent to radiotherapy in the treatment of carcinoma of the head and neck region. Local hyperthermia at 42–43°C was generated by a 27–12 MHz radiofrequency diathermy unit and was used before radiotherapy in 33 patients; the remaining 32 patients were subjected to radiotherapy alone. The response in patients with early lesions (Stage I and II) was similar for both the groups, while in patients with advanced disease (Stage III and IV) a significantly better tumour control was obtained by the use of the combined treatment