DCA
DCA metabolically targets the mitochondria, involving inhibition of mitochondrial pyruvate dehydrogenase kinase, thus leading to selective apoptosis pressures by reactive oxygen species.
DCA highlights the Warburg effect in disease.
Publication of DCA in the peer-reviewed Journal of Medical Cases
DCA may also improve health status by reducing excess lactate or lactic acid – American Journal of Physiology
DCA is a prescriptive item in Canada. People who are interested in its use need to be evaluated by a licensed healthcare professional.
Studies & further reading
Selected publications for patients who want to explore the research. Each finding applies to the study’s own population, protocol and stage of evidence; your care team can help you understand what may be relevant to you.
This review discusses metabolic features of oral cancer and the scientific rationale for studying dichloroacetate. It identifies potential research directions while emphasizing the need to translate laboratory findings into well-designed clinical trials.